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Schistosomiasis and praziquantel resistance

A study led by researchers at the London School of Hygiene and Tropical Medicine reviews the recent significant advances in understanding the molecular basis of praziquantel action and drug resistance in Schistosoma mansoni. The recent WHO treatment guidelines aim to extend and scale up mass drug administration of praziquantel in schistosomiasis endemic countries. The WHO NTD roadmap aims to achieve the elimination of schistosomiasis as a public health problem by 2030. The scale up of mass drug ...
Le Clech Merck Kga Merck Kgaa Lake Albert Saharan Africa

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Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.
United States Medical College Of Wisconsin Jonathan Marchant Winka Le Clech Tim Anderson Le Clech

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