Using protein blast and searching for Elvis, part I.
In which we search for Elvis, using blastp, and find out how old we would have to be to see Elvis in a Las Vegas club.
Source: scienceblogs.com
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Molecular characterization and genotype distribution of thioester-containing protein 1 gene in Anopheles gambiae mosquitoes in western Kenya | Malaria Journal
Evolutionary pressures lead to the selection of efficient malaria vectors either resistant or susceptible to Plasmodium parasites. These forces may favour the introduction of species genotypes that adapt to new breeding habitats, potentially having an impact on malaria transmission. Thioester-containing protein 1 (TEP1) of Anopheles gambiae complex plays an important role in innate immune defenses against parasites. This study aims to characterize the distribution pattern of TEP1 polymorphisms a...
Homa Bay Kendu Bay Saharan Africa International Center National Center Bse Ni New England Biolabs Inc Additional Malaria Research
Source: biomedcentral.com
Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties
Abstract Antimicrobial peptides form part of the innate immune response and play a vital role in host defense against pathogens. Here we report a new antimicrobial peptide belonging to the cathelicidin family, cathelicidin-MH (cath-MH), from the skin of Microhyla heymonsivogt frog. Cath-MH has a single α-helical structure in membrane-mimetic environments and is antimicrobial against fungi and bacteria, especially Gram-negative bacteria. In contrast to other cathelicidins, cath-MH suppresses c...
Source: elifesciences.org