Proguanil and atovaquone use is associated with lower colorectal cancer risk: a nationwide cohort study | BMC Medicine
Individuals with a family history of colorectal cancer (CRC) are at a high risk of developing CRC. Preclinical studies suggest that the anti-malaria drug proguanil and atovaquone might play a role in preventing CRC, but population-based evidence is still lacking. By accessing a couple of nationwide Swedish registers, we performed a cohort study to explore whether using proguanil and atovaquone might associate with a lower risk of CRC by adopting a new-user study design. Adults who have 1 or more...
Lund Dnr International Classification Of Diseases National Patient Register Regional Ethical Review Board Swedish Multi Generation Register Swedish Cancer Registry
Source: biomedcentral.com