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DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.
Lily Ramsey Madison Strine Craig Wilen Of Yale University Craig Wilen Yale University

Key regulator of COVID viral receptor may be

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues. The finding provides important new information on how the virus responsible for COVID-19 causes infection and may lead to new antiviral treatments.
United States Madison Strine Craig Wilen Of Yale University Smith Family Foundation National Science Foundation Clara Guthrie Patterson Trust

Key regulator of COVID viral receptor may be new drug target

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13 in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, U.S., and colleagues. The finding provides important new information on how the virus responsible for COVID-19 causes infection and may lead to new antiviral treatments.
Madison Strine Craig Wilen Of Yale University Patrick Lane Sceyence Studios Craig Wilen Yale University

Yale scientists map the shape of the SARS-CoV-2 genome

By Jim Shelton January 28, 2021 Share this with FacebookShare this with TwitterShare this with LinkedInShare this with EmailPrint this Left to right; Nicholas Huston, Han Wan, Madison Strine, and Rafael Araujo Tavares working in Anna Marie Pyleโ€™s lab. (Photo: Dan Renzetti) Throughout the COVID-19 pandemic, scientists have tried to understand and track SARS-CoV-2 without a proper parts list. Much of the research emphasis has been on proteins โ€” such as the โ€œspikeโ€ proteins that cover the ...
Madison Strine Nicholas Huston Rafael Tavares Tamas Horvath Ruthr Montgomery Neal Ravindra
Source: yale.edu

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