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How Huntington's Disease Affects Different Neurons

Researchers have identified how two different populations of neurons in the striatum are affected differently in Huntington's disease. The neurodegeneration of one of these populations leads to motor defects while damage to the other population located in striosomes may account for mood disorders associated with the early stages of Huntington's.
Ann Graybiel Myriam Heiman Richard Faull Sarah Mcdonnell Jessicaj Pourian Manolis Kellis

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