Pentelute Lab News Today

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Innovating at the intersection of chemistry, biology, and engineering, Professor Brad Pentelute and the MIT Pentelute Laboratory are revolutionizing

MIT Professor Brad Pentelute and his team invent new chemistry to modify proteins for efficient drug delivery into cells.

Driving into Austin, the city appears slowly, then all at once. But in between all the shiny new high rises and skyscrapers, the UT Tower still stands as recognizable as ever—a signal to students, Austinites, and visitors that big things happen here. Not even the iconic pink dome of the Texas Capitol captures the city’s—or […]

MIT chemists developed a new way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic. Using their new

MIT researchers invented a fully automated fast-flow instrument called Tiny Tides that can synthesize cell-penetrating peptide-conjugated peptide nucleic acids (PPNAs) in a single shot, significantly increasing speed and efficiency. The work could one day enable antivirals, including potentially against SARS-Cov-2.