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Understanding how to improve antibodies targeting OX40 for the treatment of cancer

Credit: NIAID Scientists at the University of Southamptons Centre for Cancer Immunology have gained new insight into how the immune system can be better used to find and kill cancer cells. Working with BioInvent International, a team led by Professor Mark Cragg and Dr Jane Willoughby from the Antibody and Vaccine Group, based at the Centre, have shown that antibodies, designed to target the molecule OX40, give a more active immune response when they bind closer to the cell membrane and can be ...
Jane Willoughby Marks Cragg Peter Franklin Mark Cragg Janee Willoughby University Of Southampton

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