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Impact of aldehydes on DNA damage and aging

Researchers at Nagoya University in Japan have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a means to counteract aging in healthy people by controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.
Yasuyoshi Oka Mayuko Shimada Yuka Nakazawa Nagoya University Tomoo Ogi Of Nagoya University Nature Cell Biology

A Breakthrough in Genome Editing: How NICER Outperforms CRISPR/Cas9

Researchers led by Osaka University develop a new gene modification technique known as NICER that significantly reduces off-target mutations in DNA. The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organismโ€™s DNA to fix mutations that caus
Shinichiro Nakada Hiroyuki Sasanuma Mayuko Shimada Yuka Nakazawa Akiko Tomita Nature Communications

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