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Novel cell therapy treatments offer promise to immune-compromised children

WASHINGTON, April 18, 2024 (GLOBE NEWSWIRE) -- In a first-of-its-kind clinical trial, researchers found that intravenous therapies made from vir...

Novel cell therapy treatments offer promise to immune-compromised children

Novel cell therapy treatments offer promise to immune-compromised children

Knowing MRD Status Can 'Increase Chance of Cure' in Blood Cancer

CURE provides access to the cancer news, latest oncology research & expert insights that serve as a guide to every stage of the cancer experience.

Sequencing of bone marrow DNA may predict leukemia relapse after CAR-T therapy with sufficient time to intervene

Bottom Line: In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

Next-Gen MRD Testing Predicts Acute Leukemia Relapse After CAR-T

Nearly all patients with detectable disease relapsed or progressed to transplant, other therapies

Sequencing of Bone Marrow DNA May Predict Leukemia Relapse After CAR-T Therapy With Sufficient Time to Intervene

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection accurately identified all patients who would eventually relapse, while other methods were less predictive, according to a study published in Blood Cancer Discovery, a journal of the American Association for Cancer Research.