Michellee Ehrlich News Today

A gene concentrated in microglia has been identified as a mechanism to the inflammation in the brain that is a key factor in the development of Alzheimer’s disease.

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

Inflammation has increasingly been identified as a significant factor contributing to Alzheimers disease, and a recent study relates this inflammation to a gene abundant in the brains clearing cells, known as microglia

Recent failed clinical trials of a drug designed to clear the mutant Huntingtin protein that causes Huntingtons disease (HD) heightens the need for new approaches for the devastating, incurable, progressive neurodegenerative genetic disorder. Scientists at the Buck Institute have found that the targeting the protein called FK506-binding protein 51 or FKBP51 promotes the clearing of those toxic proteins via autophagy, a natural process whereby cells recycle damaged proteins and mitochondria and u...