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Older patients unable to complete one-legged stance test may have high mortality risk

Middle-aged and older individuals who are unable to complete a 10-second one-legged stance test may experience a higher risk of all-cause mortality, according to published results.“The advantages of the 10-second one-legged stance test include that it is simple, and it provides rapid, safe and objective feedback for the patient and health care providers regarding static balance,”
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Source: healio.com

Genomic profiling of pediatric tumors after relapse may widen treatment options

Genomic sequencing of tumors enabled 107 patients with pediatric cancer who experienced relapse to receive an appropriate matched therapy that is not standard of care, according to study results reported in Cancer Discovery. The international MAPPYACTS precision medicine clinical trial sought to use results of genetic profiling of tumors to suggest treatments targeted to molecular alterations.
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Source: healio.com

Slings may remain most cost-effective option for displaced midshaft clavicle fractures

According to published results, surgeons should make the cost-conscious decision to treat displaced midshaft clavicle fractures with a sling compared with open reduction and internal fixation with a plate.To determine the cost-effectiveness of open reduction and internal fixation (ORIF) with a plate vs. sling for displaced midshaft clavicle fractures, Kevin C. Wall, MD, MPH, and colleagues
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Source: healio.com

Has the COVID-19 pandemic changed the perception of the HCV care cascade?

Infectious Disease News | The COVID-19 pandemic has had a significant impact on medicine in the past 2-plus years. We asked Nancy S. Reau, MD, Richard B. Capps Chair of Hepatology and professor in the department of internal medicine, division of digestive diseases and nutrition at Rush University, if it has changed the perception of the hepatitis C virus care cascade.
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Source: healio.com

FDA approves abbreviated new drug application for oral anxiety treatment

ANI Pharmaceuticals Inc. has received FDA approval of its abbreviated new drug application for clorazepate dipotassium tablets, according to a company press release.ANI stated that this is a generic version of Tranxene (clorazepate dipotassium, Sanofi), which is indicated for managing anxiety disorders, according to the FDA package insert.
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Source: healio.com

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Review of artemisinin derivatives: An artful approach to malaria treatment

Infectious Disease News | The mosquito is one of the world’s most impactful forces. The breadth of transmissible diseases caused by a mosquito bite, including malaria, has helped shape human history.Malaria is caused by infection of erythrocytes with protozoan parasites of the genus Plasmodium that are transmitted through the bites of infected female Anopheles mosquitoes. In 2020, there were an estimated 241 million
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Source: healio.com

Xcopri provides long-term seizure control in patients with focal epilepsy

Long-term use of Xcopri was safe and reduced seizures by more than 90% in adults with uncontrolled focal seizures, according to results of an open-label extension study published in Neurology. “The findings show that the notable improvement in seizure control that was seen in patients with uncontrolled focal epilepsy is sustained over long term,” Pavel Klein, MD, lead study author and
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Source: healio.com

FDA releases 5-year action plan to combat neurodegenerative diseases

The FDA on June 23 announced a 5-year strategy for improving and extending the lives of people with rare neurodegenerative diseases by advancing development of safe and effective medical products and facilitating access to novel treatments. The plan, which will serve as a blueprint for how the agency will move forward in tackling challenges in drug development, was developed in accordance with
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Source: healio.com

Non-O blood types linked to increased venous thromboembolism risk in patients with cancer

Individuals with non-O blood types had an increased risk for venous thromboembolism 3 months after a cancer diagnosis or recurrence, according to study results published in Blood Advances. Additionally, researchers noted an association of non-O blood types with an increased risk for VTE among patients with intermediate and low-risk tumor types.
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Source: healio.com

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