The SARS-Cov-2 pandemic illustrates how variable vaccines can be in their length of efficacy, with regular boosters needed to keep people protected. In comparison, the immunity generated by a single vaccination against the measles virus can last decades.
It has always remained a scientific mystery as to why only some vaccines lead to life-long protection. Now a paper published in the journal, Immunity, led by Prof. David Tarlinton and Dr Marcus Robinson, both from Monash University’s Central Clinical School in Melbourne, Australia, has found that the clue likely lies in the body producing a unique subtype of an immune cell in response to some but not other vaccinations. The finding could revolutionise how all vaccines could be made to be longer lasting.
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