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UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis Popular in aquariums all over the world, the zebrafish is native to South Asia. But here in a Cincinnati Childrens laboratory, the freshwater variant plays a vital role in scientific discovery. The iconic stripes are eye-catching but its the transparency of zebrafish embryonic tissue which are most prized by researchers like Oriana Zinani, a fifth-year doctoral student in molecular developmental biology in...
University Of Cincinnati United States Oriana Zinani Kemal Kesero Emily Henderson Cincinnati Children Hospital Medical Center

Researchers identify genetic risk factors contributing to pneumonia susceptibility and severity

Researchers identify genetic risk factors contributing to pneumonia susceptibility and severity Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Their findings, published recently in the American Journal of Human Genetics, may aid efforts to identify patients with COVID-19 at greatest risk for pneumonia, and enable earlier interventions to prevent sev...
United States New York Hsin Chen Emily Henderson Icahn School Of Medicine At Mount Sinai University Of North Carolina At Chapel Hill

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SARS-CoV-2 variants appear to arise independently of local transmission

Researchers at the University of Michigan in the United States have cautioned against only using within-host minor genetic variations to resolve the genomic epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).
United States Adam Lauring Sally Robertson Global Initiative On Sharing Avian Influenza Data University Of Michigan Global Initiative

South African SARS-CoV-2 variant escapes antibody neutralization

Researchers in South Africa have conducted a study showing that the novel 501Y.V2 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in the country is able to escape the neutralizing antibodies that are elicited by previously circulating strains of the virus.
South Africa United States United Kingdom South African Penny Moore Sally Robertson

Scientists find 2 species of human coronavirus that can evolve to evade immune system

Scientists find 2 species of human coronavirus that can evolve to evade immune system January 21, 2021 × The findings suggest that if SARS-CoV-2 evolves in the same way, current vaccines against the virus may become outdated A new study has found that two species of seasonal human coronavirus related to SARS-CoV-2 can evolve in certain proteins to evade recognition by the immune system. The findings of the study, published in the journal eLife, suggested that if SARS-CoV-2 evolves in the same...
Kathryn Kistler Infectious Disease Division Fred Hutchinson Cancer Research Center Spike Protein Corona Virus Covid 19

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