Page 112 - Mutation News Today

Date Time Researchers Demonstrate How Defects in Mitochondria May Lead to Autism Spectrum Disorder Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that autism spectrum disorder (ASD) may be caused by defects in the mitochondria of brain cells. The findings were published online by the Proceedings of the National Academy of Sciences. Multiple studies have revealed hundreds of mutations associated with autism spectrum disorder, but there is no consensus as to how the...

ETH researchers have found a gene mutation that causes the sperm of boars to immobilize. Their discovery will help pig breeders to exclude animals with...

Indias Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study The worldwide increase in the circulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the crossing of the shocking milestone of 100 million reported cases.  Among the chief causes of growth in infection numbers have been the emergence of new variants, notably the UK variant, with increased infectivity relative to the ancestral strain. However, a new preprint research paper, posted to...

Several teams of scientists around the globe have been working relentlessly to test whether antibodies from vaccinated people are less able to recognise the new virus variants.

Scientists study how different genes dance to the circadian rhythm In 2017, the Nobel Prize in Physiology or Medicine went to three scientists who uncovered the molecular mechanisms that control the circadian rhythm, otherwise known as the "wake-sleep" cycle. To carry out their work, the scientists used the common fruit fly Drosophila melanogaster, making this the sixth Nobel to be awarded to research involving it. Fruitful fruit flies Life scientists have been using Drosophila for over a cen...

New method identifies important mutations behind hereditary non-polyposis colorectal cancer Colorectal cancer is the third most common form of cancer. While 90% of cases are in people older than 50, there is an as-yet unexplained rising incidence in younger people. Family history ranks high among risk factors for developing colorectal cancer, and people with such a history are often advised to get more frequent screening tests or start screening sooner than the recommended age of 45 years old. ...

Janssen: New Amivantamab Data from CHRYSALIS Study Show Robust Clinical Activity and Durable Responses in Patients with Metastatic or Unresectable Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Mutations FOR EU TRADE AND MEDICAL MEDIA ONLY Not for distribution in the UK and Benelux The Janssen Pharmaceutical Companies of Johnson Johnson today announced new data from the Phase 1 CHRYSALIS study, which evaluated amivantamab in patients with metastatic or unresectable non-small cell lung ca...

With cities around the globe locking down yet again amid soaring COVID-19 numbers, could seasonality be partially to blame? New research from the University of Illinois says yes.

Innovative breakthrough promises to diagnose DNA rearrangement mutations Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities. However, an innovative breakthrough developed by researchers at Virginia Commonwealth University Massey Cancer Center and the VCU Department of Physics promises to diagnose DNA rearrangement mut...

  Deputy Prime Minister Vũ Đức Đam chaired the National Steering Committee for COVID-19 Prevention and Control meeting on the new community cases. — Photo from the Ministry of Health HÀ NỘI — Two community infections of COVID-19 have been confirmed in Việt Nam, the first local transmissions for almost two months. One of the new cases is linked to a woman who tested positive for the new variant of coronavirus after arriving in Japan to work earlier this week. It has not yet ...