Page 111 - Mutation News Today

Gene panel test enables highly accurate diagnosis of liposarcomas Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma. It quickly and reliably distinguishes benign lipomas from liposarcomas and can be performed in laboratories at a lower cost than current "gold standard" tests. The new assay is described in The Journal of Molecular Diagnosis, ...

Study shows how genetic mutations lead to kidney cysts in tuberous sclerosis complex Tuberous sclerosis complex (TSC) afflicts as many as two million people around the world, affecting multiple organs, including lungs, brain, skin, and kidneys. In about 80 percent of cases, it causes cysts and benign tumors to form in the kidney, eventually resulting in kidney failure. Its known that the disease is triggered by genetic mutations, but how these mutations lead to the formation of kidney cysts has...

By Luke Hanrahan

Vaccine manufacturers are looking at how to improve vaccine to be ready for any variant

Scientists unravel the workings of a mysterious protein implicated in movement disorders Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders. The findings, which appear in Cell Reports, are an advance in the basic understanding of how the brain controls muscles and could lead to treatments for children born with Gαo-mutation movement disorders...

Research could open the door to next-generation of cancer drugs that work better Some of the most commonly used drugs for treating hereditary breast and ovarian cancers may not work the way we thought they did, according to new University of Colorado Boulder research. The paper, published February 2 in the journal Nature Communications, sheds new light on how they do work and could open the door to new next-generation medications that work better, the authors said. Despite the success of these...

The coronavirus variant first found in the UK and spreading around the world appears to be evolving a mutation that scientists fear could help the virus evade vaccines.

Gene mutations may explain the poorer outcomes in Hispanic and Latino children with leukemia A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine researchers. They said a novel therapeutic drug combination – as well as testing for these mutations – may help address the disparity. Hispanic and Latino children are between 1.2 and 1.75 times more likely to ...

Million doses to 6,500 pharmacies across the u.s. next week. so, how will this work? and scientists in the uk tonight, after already dealing with the uk variant, now warning of another possible mutation similar to the brazilian and south african strains. so, what does this mean about what we could see here? the impeachment trial of former president trump set to begin one week from today. what his lawyers submitted today. how they plan to defend the former president. as house democrats reveal t...

The white house announcing shipments of vaccines will begin going straight to select pharmacies starting next week. >> this pharmacy program will expand access in neighborhoods across the country, so you can make an appointment and get your shot conveniently and quickly. >> reporter: for now, some 6,500 pharmacies around the country will receive a total of 1 million doses of vaccine. crucial to combat more contagious variants now emerging. british officials going door-to-door, testing. >> is it ...