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Researchers have developed a computational method to map the architecture of human tissues in unprecedented detail

Researchers assessed a novel method for bacterial cell segmentation named Omnipose.

Get latest articles and stories on Science at LatestLY. A new advance overcomes present limitations in spatial transcriptomics with a DNA nanotechnology-driven method called Light-Seq. Light-Seq allows researchers to geotag the full repertoire of RNA sequences with unique DNA barcodes exclusive to a few cells of interest. These target cells are selected using light under a microscope via a fast and effective photocrosslinking process, and their RNAs made available to next-generation sequencing w...

A new advance overcomes present limitations in spatial transcriptomics with a DNA nanotechnology-driven method called Light-Seq. Light-Seq allows researchers to geotag the full repertoire of RNA sequences with unique DNA barcodes exclusive to a few cells of interest

Harvard University researchers use “Light-Seq” method for full-transcriptome sequencing of hard-to-access cells.

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.

The brain is a complex organ, and no one imaging mode can catch everything that's going on inside it. Over the years, multiple "brain maps" have emerged, each focusing on different brain processes, from metabolism to cognitive function.

Macrophages are immune cells that engulf and digest pathogens, cancer cells or cellular debris. The kidneys -; like other tissues in the body -; contain kidney resident macrophages, or KRMs, from the time of birth.

The technique of visualizing the 3D structure of the brain’s biological tissues is particularly important for understanding the ...

Biophysicists at École Polytechnique Fédérale de Lausanne (EPFL) introduced a method to automate microscope control for imaging b