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Scientists Pinpoint Structure of Antifungal, Challenge Binding Mechanism

Nearly seventy years after the discovery of Amphotericin B, scientists are still learning from this enigmatic drug. New results challenge a long-standing paradigm for the drug's mechanism of action and suggest new avenues for drug development.
Taras Pogorelov Martin Burke National Institutes Of Health Morgridge Institute For Research University Of Illinois At Urbana Champaign National Magnetic Resonance Facility At Madison
Source: wisc.edu

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University of Illinois: Atomic structure of antifungal drug confirms unusual mechanism, opens door to less-toxic derivatives

Advanced molecular imaging technology has now mapped the structure of a drug widely used to treat fungal infections but whose workings have mystified researchers and physicians for nearly 70 years.In a new study, researchers at the University of Illi
United States University Of Wisconsin University Of Illinois Taras Pogorelov Martind Burke Agnieszka Lewandowska

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