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Blocking key protein normalizes uterine muscle tone, study shows

Abnormal uterine blood flow is a hallmark of hypertensive disorders of pregnancy, including chronic hypertension, preeclampsia and gestational hypertension. Abnormal uterine blood flow is also associated with a low fertility rate. However, the mechanisms controlling uterine blood flow regulation, both in nonpregnant and pregnant states, are poorly understood.
Bo Sun Phosphodiesterases Mediate Myogenic Constriction Inhibitoryg Protein Signaling Negatively Modulated Dual Action

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