Nir Yosef News Today

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting. In a new stud

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting. In a new stud

<p>In a new study published today in <em>Cell</em>, researchers from Prof. Ido Amit's lab at the Weizmann Institute of Science have managed for the first time to develop a method for tracking and measuring changes over time on in single cells inside the body. The method, called Zman-seq (from the Hebrew word <em>zman</em>, for “time”), consists of labeling cells with different time stamps and tracking them in healthy or pathological tissu...

Family trees of lung cancer cells, built using CRISPR-based lineage tracing, reveal how cancer evolves from its earliest stages to become aggressive and capable of spreading throughout the body.

Over time, cancer cells can evolve to become resistant to treatment, more aggressive, and metastatic — capable of spreading to additional sites in the

CRISPR-Based Cancer Cell Lineage Tracing Offers Insights into Drivers of Metastasis January 22, 2021 Source: Science Photo Library - Moredun Animal Health Ltd/Getty Images A new CRISPR-based method for tracing real-time cancer progression across thousands of cells has revealed novel insights into the rates, routes, and drivers of cancer metastasis. Using the lineage-tracing technique, Whitehead Institute member Jonathan Weissman, PhD, and colleagues were able to treat cancer cells in much the s...

Massachusetts Institute of Technology When cancer is confined to one spot in the body, doctors can often treat it with surgery or other therapies. Much of the mortality associated with cancer, however, is due to its tendency to metastasize, sending out seeds of itself that may take root throughout the body. The exact moment of metastasis is fleeting, lost in the millions of divisions that take place in a tumor. “These events are typically impossible to monitor in real time,” says Jonathan W...

 E-Mail IMAGE: Each color represents a different location in the body. A very colorful tree shows a highly metastatic phenotype, where a cells descendents jumped many times between different tissues. A tree... view more  Credit: Jeffrey Quinn/Whitehead Institute When cancer is confined to one spot in the body, doctors can often treat it with surgery or other therapies. Much of the mortality associated with cancer, however, is due to its tendency to metastasize, sending out seeds of it...