Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy
The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.
Source: news-medical.net
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Revving up COVID mRNA vaccines: Algorithm generates 128-fold increase in antibodies
Research paper proposes a new method for predicting highly expressed genes based on codon usage bias and minimum free energy of mRNA secondary structures. The method involves constructing a stochastic grammar that generates sequences with high CAI and low MFE, and testing it on two mRNA vaccines.
Neha Mathur Eric Topol Erictopol Neha Mathurmay Improves Stability Image Credit Codon Adaptation Index
Source: news-medical.net
Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses
Researchers conducted a forensic analysis of SARS-CoV-2-related coronaviruses (SARS2r-CoVs).
Andrii Vodolazhskyi Shutterstock Research Square Coronavirus Disease Covid 19 Ars Cov 2 Oding Region Covid 19
Source: news-medical.net
Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques
Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques.
Source: news-medical.net
Evolution of the SARS-CoV-2 omicron variant
Study shows that the omicron variant shares a common ancestry with the VOI lambda and has evolved mainly because of non-synonymous mutations.
South Africa World Health Organisation Image Credit Coronavirus Disease Covid 19 Ars Cov 2 Oding Region
Source: news-medical.net