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Ultrasound guided lavage with corticosteroid injection versus sham lavage with and without corticosteroid injection for calcific tendinopathy of shoulder: randomised double blinded multi-arm study

Objective To compare treatment effects between ultrasound guided lavage with corticosteroid injection and sham lavage with and without corticosteroid injection in patients with calcific tendinopathy of the shoulder. Design Pragmatic, three arm, parallel group, double blinded, sham controlled, randomised, superiority trial with repeated measurements over 24 months. Setting Six hospitals in Norway and Sweden. Participants 220 adults with calcific tendinopathy of the shoulder, persistent for at lea...
Eteläuomen Läi United Kingdom Jesper Blomquist Aase Bye Marius Ekeberg Trygve Jb Hoffs
Source: bmj.com

Evidence for clinical interventions targeting the gut microbiome in cardiometabolic disease

Tarini Shankar Ghosh and Ana Maria Valdes evaluate the evidence for clinical effects of microbiome altering interventions on cardiometabolic traits ### Key messages Cardiometabolic diseases are one of the main causes of morbidity and mortality in western countries and are increasing in low and middle income countries.1 Dietary intake is one of the main determinants of cardiometabolic health1 and of microbiome composition.2 The gut microbiome is known to play an important part in the development ...
United States Dariush Mozaffarian Rachael Hinton Emma Veitch Navjoyt Ladher David Ludwig
Source: bmj.com

Challenges of obesity and type 2 diabetes require more attention to food environment

The narrative must shift away from individual choice on to structural factors Over half of the global population will be living with overweight or obesity by 2035 if current trends continue, and more than 1.3 billion people worldwide will have diabetes by 20501; type 2 diabetes will account for most of the new cases, fuelled by changes in obesity and dietary risks.2 These trends are likely to have serious health, social, and economic effects, not least for low and middle income countries, which...
David Ludwig Emma Veitch Navjoyt Ladher Nita Forouhi Dariush Mozaffarian Rachael Hinton
Source: bmj.com

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Social, clinical, and policy implications of ultra-processed food addiction

Conceptualising ultra-processed foods high in carbohydrates and fats as addictive substances can contribute to efforts to improve health, argue Ashley Gearhardt and colleagues The scientific understanding of addiction is evolving. Although addiction to certain foods is not included in diagnostic frameworks such as the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), research on this topic has grown rapidly in the past 20 years. Much of this research uses the Yale Food Addiction Sc...
United States Ashleyn Gearhardt Christinaa Roberto Nita Forouhi Nassibb Bueno Rachael Hinton
Source: bmj.com

High but decreasing prevalence of overweight in preschool children: encouragement for further action

Sarah Maessen and colleagues argue that identifying successful policies and practices in countries with falls in early childhood overweight can help enhance efforts and reduce within country inequities Nearly every country worldwide has experienced a steady rise in the prevalence of obesity across all age groups in recent decades.1 However, there has been recent optimism about an apparent plateau in prevalence of unhealthy weight among children in some high income countries, particularly among y...
South Africa United Kingdom United States New Zealand South African Sarahe Maessen
Source: bmj.com

Interwoven challenges of covid-19, poor diet, and cardiometabolic health

Carmen Piernas and Jordi Merino argue that suboptimal diet and poor metabolic health aggravated the covid-19 pandemic and require greater attention to increase population resilience and reduce health inequalities The covid-19 pandemic emerged at a time when many countries were already grappling with unprecedented levels of obesity and cardiometabolic disease.1 Underlying poor metabolic health, unhealthy diets, and increased health inequalities compounded the pandemic’s economic, public health,...
United Kingdom Dariush Mozaffarian Rachael Hinton Ramony Cajal Jordi Merino Nita Forouhi
Source: bmj.com

Nutrition could prevent or promote non-alcoholic fatty liver disease: an opportunity for intervention

Manuel Romero-Gómez and colleagues discuss how diet and modifiable factors can help prevent of non-alcoholic fatty liver disease and the importance of engaging all society through awareness, education, and policy change ### Key messages Non-alcoholic fatty liver disease (NAFLD) is characterised by fat accumulation in hepatocytes in people who drink little or no alcohol and is strongly related to metabolic disorders like obesity, type 2 diabetes, dyslipidaemia, and arterial hypertension.1 The gl...
United States United Kingdom Navjoyt Ladher David Ludwig Franz Mart Cienciae Innovaci
Source: bmj.com

Ultra-processed foods and cardiometabolic health: public health policies to reduce consumption cannot wait

Incomplete understanding of the multiple mechanisms underlying the link between ultra-processed foods and cardiometabolic health should not be an excuse for inaction argue Mathilde Touvier and colleagues The effect of diet on health has historically been considered from a nutrient based perspective—for example, excess total fat, saturated fat, dietary cholesterol, calories, sugar, or salt and lack of dietary fibre, vitamins, and minerals.1 More recently, this approach has been complemented by...
Sri Lanka United Kingdom Romania General United States Mathilde Touvier Emma Veitch
Source: bmj.com

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