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Critical examination of incorporating prescription psychostimulants into the continuum of care for people with stimulant use disorder in Canada

In a recent article published in CMAJ , Drs. Palis and McDonald[1][1] present evidence from a systematic review to support a claim that prescription psychostimulants are not associated with serious adverse events in patents with stimulant use disorders.[2][2] Although this review offers valuable
Open Access Creative Commons Attribution
Source: cmaj.ca

Early versus delayed antihypertensive treatment in patients with acute ischaemic stroke: multicentre, open label, randomised, controlled trial

Objectives To compared the effect of early antihypertensive treatment started within 24-48 h of stroke onset versus delaying treatment until day eight on reducing dependency or death. Design Multicentre, randomised, open label trial. Setting 106 hospitals in China between 13 June 2018 and 10 July 2022. Participants 4810 patients (≥40 years) were enrolled with acute ischaemic stroke within 24-48 h of symptom onset and elevated systolic blood pressure between 140 mm Hg and <220 mm Hg. Interve...
Monte Carlo Shenzhen Kangzhe Pharmaceutical Co National Institutes Of Health Data Coordinating Center Institutional Review Board Of Tulane University Technology Of China
Source: bmj.com

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Interactive effects of ambient fine particulate matter and ozone on daily mortality in 372 cities: two stage time series analysis

Objective To investigate potential interactive effects of fine particulate matter (PM2.5) and ozone (O3) on daily mortality at global level. Design Two stage time series analysis. Setting 372 cities across 19 countries and regions. Population Daily counts of deaths from all causes, cardiovascular disease, and respiratory disease. Main outcome measure Daily mortality data during 1994-2020. Stratified analyses by co-pollutant exposures and synergy index (>1 denotes the combined effect of pollut...
Hong Kong Soult Ukpyolsi South Korea Collaborative Research Network National Natural Science Foundation Of China University Of Florence
Source: bmj.com

Mortality risks associated with floods in 761 communities worldwide: time series study

Objective To evaluate lag-response associations and effect modifications of exposure to floods with risks of all cause, cardiovascular, and respiratory mortality on a global scale. Design Time series study. Setting 761 communities in 35 countries or territories with at least one flood event during the study period. Participants Multi-Country Multi-City Collaborative Research Network database, Australian Cause of Death Unit Record File, New Zealand Integrated Data Infrastructure, and the Internat...
New Zealand City Of United Kingdom Czech Republic United States South Australia
Source: bmj.com

New Translation: "Haiti for the Haitians" – Repeating Islands

Edited by Brandon R. Byrd and Chelsea Stieber, and translated by Nadève Ménard, Louis-Joseph Janvier’s Haiti for the Haitians was published by Liverpool University Press on October 1, 2023. It is the first major English translation of Janvier, one of the foremost Haitian intellectuals and diplomats of the late nineteenth and early twentieth centuries. It…
Brandonr Byrd Kathrynb Gore Michel Rolph Trouillot Louis Joseph Janvier Lyonel Trouillot Chelsea Stieber

Changes in exposure to ambient fine particulate matter after relocating and long term survival in Canada: quasi-experimental study

Objective To investigate the association between changes in long term residential exposure to ambient fine particulate matter (PM2.5) and premature mortality in Canada. Design Population based quasi-experimental study. Setting Canada. Participants 663 100 respondents to the 1996, 2001, and 2006 Canadian censuses aged 25-89 years who had consistently lived in areas with either high or low PM2.5 levels over five years preceding census day and moved during the ensuing five years. Interventions Ch...
United States Aaron Van Donkelaar Megan Kirby Mcgregor Jays Kaufman Li Bai Lauren Pinault
Source: bmj.com

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