Page 23 - Ouse Model News Today

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to virtually all types of treatment, including newer immunotherapies.

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

An anti-inflammatory drug candidate, known as 3,6'-dithiopomalidomide (DP), designed by researchers at the National Institute on Aging, protected lab mice against cognitive decline by reducing brain inflammation.

T and B lymphocytes, which are part of a group of immune cells commonly called white blood cells, work together to eliminate foreign invaders in the body such as viruses.

Getting a good night's sleep can sometimes be a challenge, but inflammation may make it even more difficult.

Researchers from Tokyo Medical and Dental develop artificial tendons in vitro from human stem cells that could fix common tendon injuries such as Achilles tendon rupture.

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

Cell death plays an important role in normal human development and health but requires tightly orchestrated balance to avert disease. Too much can trigger a massive inflammatory immune response that damages tissues and organs. Not enough can interfere with the body's ability to fight infection or lead to cancer.

A joint study by Nanyang Technological University, Singapore and National University of Singapore (NUS) scientists has examined why, in mice, female brains are more predisposed to Alzheimer's disease and other neurodegenerative diseases.