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Study identifies the role of a key cell receptor in efferocytosis after ischemic stroke

It's clear that taking out the trash is an essential process in maintaining a clean and tidy home. But did you know that your body has a similar process for waste removal in which damaged cells are "thrown out"? A research team in Japan has recently shed new light on the dynamics of this process—termed efferocytosis—following ischemic stroke.
Akira Shibuya Emily Henderson University Of Tsukuba Science Immunology Ischemic Stroke Ouse Model

New class of CXCR4 antagonists could prevent airway inflammation and atopic dermatitis

Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist andinverse agonistof CXCR4 and is a promising compound for the development of improved analogues for the therapy of CXCR4-associated diseases.
Emily Henderson Airway Inflammation Atopic Dermatitis Ouse Model

High fat diet exacerbates Alzheimer's disease in mouse model

Research has shown that individuals who have diabetes are more prone to develop dementia. Although people are widely aware of diabetes, owing to its common occurrence, they are less aware of prediabetes. Similar to diabetes, prediabetes is also associated with impaired glucose tolerance. However, unlike diabetes, patients with prediabetes show a slight increase in insulin and fasting blood glucose rather than hyperglycemia.
Priyom Bose Fat Diet Creative Commons Attribution Alzheimer 39s Disease Ouse Model Neurodegenerative Diseases

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Glycerin helps calm the red itchy patches in psoriasis model

Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combatting their psoriasis and now scientists have objective evidence to support their reports.
United States Wendy Bollag Emily Henderson College Of Georgia International Journal Of Molecular Sciences Charlie Norwood Va Medical Center

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