Page 28 - Ouse Model News Today

The brain is not a passive recipient of injury or disease. Research has shown that when neurons die and disrupt the natural flow of information they maintain with other neurons, the brain compensates by redirecting communications through other neuronal networks.

It's often cancer's spread, not the original tumor, that poses the disease's most deadly risk.

An international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.

Apart from lifestyle interventions, there are currently no approved treatments for NASH. A liver transplant is sometimes the only remedy.

DNAM-1 receptor could be used as new molecular target for treating autoimmune diseases Autoimmune diseases occur when an individuals immune system fights their own body as if it was a foreign invader. However, in healthy people, these responses are prevented by a process known as immune tolerance. Many complex biological mechanisms maintain the necessary balance between immune activation and suppression to ensure immune tolerance does not prevent the body from effectively fighting pathogens. In...

Unique pre-clinical model enables study of HIV infection and testing of new therapies A team led by researchers at Weill Cornell Medicine and Childrens National Hospital has developed a unique pre-clinical model that enables the study of long-term HIV infection, and the testing of new therapies aimed at curing the disease. Ordinary mice cannot be infected with HIV, so previous HIV mouse models have used mice that carry human stem cells or CD4 T cells, a type of immune cell that can be infected ...

Many natural compounds have various anti-inflammatory and other beneficial properties that humans have been utilizing for medicinal purposes for hundreds of years.

Researchers use gene therapy to prevent learning, memory loss in Alzheimers mouse model Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimers disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease. The findings are published online in advance of the June 11, 2021 issue of Molecular Therapy-Methods & Clinical D...

Blood-brain barrier and its effect on the immune system play a role in schizophrenia Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally. That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Childrens Ho...

POT1 gene linked to glioma development mediates its effects in a sex-specific manner Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. Researchers found that female mice with glioma that lacked the gene survived less than males. This led them to investigate human glioma cells, where they found ...