Partillion Bioscience News Today

UCLA stem cell scientists find surprise genetic instructions for boosting protein secretion, with big implications for biotechnology and cell therapy.

A collaboration led by UCLA and the Seattle Children's Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.

Researchers studying white blood cells identified an atlas of genes linked to high production and release of the most common type of antibody found in the human body, known as immunoglobulin G. The finding could be a step toward new antibody-based treatments and improvements in the effectiveness of cell therapies. The researchers used microscopic containers called nanovials, which were developed at UCLA, to capture the individual cells they studied.

The discovery was made possible by UCLA-developed nanotechnology.

In this application note, Luminex describes a novel method involving a uniform hydrogel particle platform, created by Partillion Bioscience, called nanovial. Imaging flow cytometry is then used to simultaneously measure the individual cellular characteristics and secretions released from each specific cell.

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.Efforts to develop and

Drugmakers have been using genetically modified cells as small drug factories for over 40 years. These cells can be instructed to produce chemicals that can be utilized to treat cancer and autoimmune diseases like arthritis.

The advance could have implications for drug development and biological research.

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

Di Carlo Lab/UCLA California NanoSystems Institute Bowl-shaped microparticles can be useful for capturing and analyzing individual cells or cell