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NETRIS Pharma Doses First Patient in Pancreatic Cancer Clinical Study with NP137

Lap-NET1 study will evaluate safety and efficacy of anti-netrin-1 antibody NP137 in combination with m_FOLFIRINOX as first-line treatment in patients with locally advanced pancreatic ductal adenocarcinoma March 29th, 2023 LYON, France —NETRIS Pharma, a clinical-stage private biopharmaceutical company developin...
Patrick Mehlen Centre Hospitalier Universitaire Grenoble Alpes Gael Roth Western Europe Principal Investigator

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How blood stem cells maintain their lifelong potential for self-renewal

 E-Mail A characteristic feature of all stem cells is their ability to self-renew. But how is this potential maintained throughout life? Scientists at the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine* (HI-STEM) have now discovered in mice that cells in the so-called "stem cell niche" are responsible for this: Blood vessel cells of the niche produce a factor that stimulates blood stem cells and thus maintains their self-ren...
Baden Wuberg Patrick Mehlen Claudia Korn Nina Cabezas Wallscheid Andreas Trumpp Benjamin Gibert Agnes Hotz Wagenblatt

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