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Pegylated interferon lambda shows good efficacy against COVID-19

In a recent study published in The New England Journal of Medicine, researchers used the TOGETHER platform trial protocol to perform a phase III randomized controlled trial (RCT) to evaluate the effectiveness of pegylated interferon (IFN) lambda (λ) therapy in outpatients with coronavirus disease 2019 (COVID-19) in Canada and Brazil.

World health organizationNew england journalEarly treatmentPegylated interferon lambdaImage creditIndustry focusCoronavirus disease covid 19Ars cov 2Evere acute respiratoryEvere acute respiratory syndrome

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COVID Treatment Shows Encouraging Results in Trial, Study Says

It involves one dose of pegylated interferon lambda, a synthetic version of a naturally occurring protein that infected cells secrete to defend against viral infection

United statesJeffrey glennPandemic preparedness initiativeDrug administrationStanford universityNew england journalStanford biosecurityPandemic preparednessEiger biopharmaceuticalsPalo altoScience healthOvid 19 pandemicCovid 19Pegylated interferon lambda

Phase 3 Trial Reports Promising Results for New COVID Treatment

The data look quite promising and other treatments have now fallen by the wayside, said Paul Sax, MD, of Brigham and Women s Hospital in Boston.

New yorkUnited statesPaul saxUniversity of torontoNew york timesMedscape coronavirus resource centerDrug administrationCoronavirus resourceCalifornia based eigerNew england journalJordan feldNew york timesreportedEiger biopharmaceuticalsPegylated interferon lambdaStates todayEngland journal

Eiger BioPharmaceuticals (EIGR) Announces NEJM Publishes Positive Phase 3 TOGETHER Results with Peginterferon Lambda in COVID-19

Eiger BioPharmaceuticals (EIGR) Announces NEJM Publishes Positive Phase 3 TOGETHER Results with Peginterferon Lambda in COVID-19
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Minas geraisGilmar reisPontifical catholic university of minas geraisHospital research instituteProfessor of medicine mcmaster universityEiger biopharmaceuticals incProfessor of medicine at university torontoNew england journalEarly treatmentPegylated interferon lambdaLead investigatorAssociate professorMedicine mcmaster universityPontifical catholic universityJordan feldSenior scientist