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FDA Clears Investigational New Drug Application for TCR-NK Cell Therapy in Multiple Myeloma

The FDA has issued a ‘safe to proceed’ for the investigational new drug application enabling a phase 1 study evaluating NY-ESO-1 TCR/IL-15 NK, a first-in-class engineered T-cell receptor natural killer cell therapy for patients with relapsed/refractory multiple myeloma.
United States Sally Cooper Murray Lachlan Mackinnon Adrian Woolfson Katy Rezvani Department Of Stem Cell Transplantation

IO-108 Demonstrates Safety and Efficacy in Advanced Solid Tumors

Findings from a phase 1 study showed that the fully humanized IgG4 antibody IO-108 was well tolerated and displayed durable responses when given as a monotherapy as well as in combination with pembrolizumab, supporting further development of the agent alone or with PD-1/PD-L1 targeted therapy for patients with advanced solid tumors.
United States Matthewh Taylor Providence Cancer Institute Melanoma Program Providence Cancer Institute Thyroid Program Developmental Cancer Therapeutics Laboratory Research Institute

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Moderna Starts New COVID-19 Vaccine Trial

Moderna Starts New COVID-19 Vaccine Trial by Angela Mohan on  March 17, 2021 at 2:17 PM First participants have been dosed in the Phase 1 study of mRNA-1283, Modernas next generation COVID-19 vaccine candidate, which will assess the safety and immunogenicity of mRNA-1283. "We are pleased to begin this Phase 1 study of our next generation COVID-19 vaccine candidate, mRNA-1283," said Stéphane Bancel, Chief Executive Officer of Moderna. "Our investments in our mRNA platform hav...
Chief Executive Officer Receptor Binding Domain N Terminal Domain India Achieves Preferred Greeting Myths Debunkedcoronavirusindian Namaste

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