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SARS-CoV-2 variants have higher transmissibility and a longer infectious period

Researchers analyzed data on three variants of concern and found that viral loads were higher and infection lasted longer for the B.1.1.7 variant. They all were more infectious than the original strain, and transmissibility also depended on population demographics.
Lakshmi Supriya Phd May Image Credit Ars Cov 2 Coronavirus Disease Covid 19 Evere Acute Respiratory

Researchers identify a novel SARS-CoV-2 variant (with the V1230L mutation) in West Bengal, India

Researchers identify a novel SARS-CoV-2 variant (with the V1230L mutation) in West Bengal, India Researchers analyzed 2,000 viral genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – sequences obtained from India and found a new variant that could be more infectious and transmissible. The continued transmission of SARS-CoV-2 has led to its mutating several times. Many of the new mutations are on the virus spi...
United Kingdom South Africa United States Lakshmi Supriya Phd May West Bengal

Researchers develop a method to detect SARS-CoV-2 and variants simultaneously

Researchers develop a method to detect SARS-CoV-2 and variants simultaneously Researchers demonstrate a method of detecting the presence and mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus using the smaller and cheaper Oxford Nanopore sequencer, a method they believe could make pandemic surveillance faster and cheaper. The coronavirus disease 2019 (COVID-19) pandemic has led to great research efforts in viral diagnostics. New methods have been developed to r...
France General United Kingdom Lakshmi Supriya Oxford Nanopore Minion Oxford Nanopore Technology Saclay University

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Why COVID-19 patients have more pathogenic bacteria in their noses

Researchers compared the nasal microbiome of coronavirus disease 2019 (COVID-19) patients, healthy individuals, and healthcare workers. These studies indicated an increase in the pathogen Pseudomonas aeruginosa present in the nasal microbiome of COVID-19 patients, which may be responsible for other secondary infections.
University Of California Irvine United States Lakshmi Supriya Kruskal Wallis Christoph Burgstedt Shutterstock Phd May

Do mixed COVID-19 vaccines provide immunity?

Do mixed COVID-19 vaccines provide immunity? The initial results of the CombivacS trial found that the antibody levels in individuals increased by 150 times when the Pfizer messenger ribonucleic acid (mRNA) vaccine was given after a first dose of the AstraZeneca severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, with only mild common side effects. Introduction The AstraZeneca coronavirus disease 2019 (COVID-19) vaccine was suspended by several countries in the European Union ...
United Kingdom Lakshmi Supriya European Union Health Institute Phd May Clinical Trial

B.1.1.7 not associated with change in serial interval of COVID-19

B.1.1.7 not associated with change in serial interval of COVID-19 With data obtained from the Virus Watch study in England and Wales, researchers found that the serial interval of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is broadly similar to estimates from previous studies and there is no evidence that the B.1.1.7 variant is associated with any change. Serial interval is a key parameter in epidemiological studies of infectious diseases. It is an estimation of the spread of ...
United Kingdom Lakshmi Supriya Phd May Virus Watch Image Credit Corona Virus

A SARS-CoV-2 vaccine candidate based on B.1.351 spike trimer shows broad neutralizing capability

A SARS-CoV-2 vaccine candidate based on B.1.351 spike trimer shows broad neutralizing capability Researchers tested a vaccine candidate in mice with up to three doses and found it produces high levels of antibodies against both SARS-CoV-2 variants of concern and the original virus strain. The emergence of several new mutations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to concerns about increased transmissibility of the virus and the ability of vaccines to prot...
South Africa United Kingdom Lakshmi Supriya Phd May Coronavirus Disease Covid 19 Ars Cov 2

Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2)

Study reports new monoclonal antibodies with broad neutralizing capabilities against betacoronaviruses (including SARS-CoV-2) The monoclonal antibodies identified target the S2 subunit of the virus spike protein and inhibit viral infection by preventing membrane fusion. Coronaviruses are pathogens found in many birds and mammals like bats, pangolins, and pigs. There have been many instances of these viruses spilling over to humans, indicating they have a broad capability to spread between many...
Lakshmi Supriya Phd May Middle East Coronavirus Disease Covid 19 Ars Cov 2 Ers Cov

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