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Merck Receives Priority Review from FDA for New Biologics License Application for Sotatercept, an Activin Signaling Inhibitor to Treat Adults with Pulmonary Arterial Hypertension (PAH)

Application based on clinically meaningful results from the Phase 3 STELLAR trial If approved, sotatercept would be the first in its class, bringing a novel approach to address a rare and...
United States Joerg Koglin Statement Of Merck Co Inc Merck Co Inc European Medicines Agency Drug Administration

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Merck's Investigational Activin Signaling Inhibitor Sotatercept Improved Six-Minute Walk Distance by 40.8 Meters at Week 24 Versus Placebo in Adults with Pulmonary Arterial Hypertension on Background Therapy

Sotatercept demonstrated statistically significant improvements in 8 of 9 secondary measures, including reduction in risk of clinical worsening or deathResults presented today at ACC.23/WCC and published in The New England Journal of MedicineRAHWAY, N.J.--(BUSINESS WIRE)--$MRK #MRK--Merck (NYSE: MRK), known as MSD o...
United States Julie Cunningham Marius Hoeper Peter Dannenbaum Damini Chokshi Merck Research Laboratories

Frontiers | Three-Dimensional Dispersion of Neutral "Plastic" Particles in a Global Ocean Model

The fate of plastics entering the 3D ocean circulation from rivers discharge is examined through the Lagrangian analysis of neutrally buoyant particles. Particles are released continuously over 1991-2010 at the surface along the coasts according to monthly estimates of rivers plastic waste input. They are advected by daily currents from a state-of-the-art global ocean model at 1/12° resolution. At the end of the simulation, particles remaining in the surface layer of 1~m thickness represent...
Gulf Of Guinea Oceans General United States France General Provence Alpes Cรดd Azur Southern Ocean

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