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Study illuminates how patients with variants in the PTPN2 gene develop IBD

Inflammatory bowel disease, or IBD, describes Crohn's disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune disorder -; a condition in which the body's immune system attacks healthy tissues.
United States University Of Southern California Lars Eckmann Marianner Spalinger Vinicius Canale Elaine Hanson

Getting It Right

This latest work is part of an ongoing effort to improve surgical care in sub-Saharan Africa, where 93 percent of the population lacks access to safe, effective, and timely surgical, obstetric, and anesthesia care. That puts the region at the epicenter of a global crisis that leaves 5 billion people without the lifesaving surgical care needed to treat injuries and disease, according to the 2015 Lancet Commission on Global Surgery. Studies find high levels of excess morbidity and mortality res...
Pritha Chatterjee Ntuli Kapologwe Sarah Maongezi Shehnaz Alidina John Meara Nutrition Service

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