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Dual-Action Drug Produces Positive Results in Patients With Advanced Neuroendocrine Tumors, Trial Finds

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.
United States Jennifer Chan Jeffrey Meyerhardt National Institutes Of Health Alliance For Clinical Trials In Oncology National Cancer Institute

Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.
United States Jennifer Chan Jeffrey Meyerhardt Lily Ramsey Rectal Cancer Center At Dana Farber Dana Farber Cancer Institute

Exelixis Announces Positive Results from Phase 3 CABINET Pivotal Trial Evaluating Cabozantinib in Advanced Pancreatic and Extra-Pancreatic Neuroendocrine Tumors

– CABINET trial will be unblinded and stopped early due to a dramatic improvement in efficacy per a unanimous recommendation by The Alliance for Clinical Trials in Oncology independent Data and...
Jennifer Chan Program In Carcinoid Exchange Commission National Clinical Trials Network National Cancer Institute Cancer Therapy Evaluation Program

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Cabozantinib Efficacy Prompts CABINET Trial Unblinding in Advanced Pancreatic and Extra-Pancreatic NETs

Interim data from the phase 3 CABINET trial demonstrated significant improvement in progression-free survival with cabozantinib vs placebo in patients with advanced pancreatic or extra-pancreatic neuroendocrine tumors following progression on prior systemic therapy.
United States Jennifer Chan Gastrointestinal Cancer Center Program In Carcinoid Neuroendocrine Tumors At Dana Farber Cancer Institute Drug Administration

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