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Comprehensive analysis of immune checkpoint inhibitors reveals endocrine toxicity patterns

Announcing a new publication for Acta Materia Medica journal. Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but pose a challenge of immune-related adverse events (irAEs), particularly endocrine toxicity, that can severely compromise patient well-being.
Compuscript Ltd Acta Materia Medica Cancer Treatment Ell Death Programmed Cell Death

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Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, ac...
New York United States Judith Klein Seetharaman Lokender Kumar Jose Pedro Friedmann Angeli Shoolini University In Solan Himachal Pradesh

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.
Peakstock Shutterstock Image Credit Colorectal Cancer Fecal Microbiota Transplantation Ell Death Growth Factor

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