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Epigenetic changes prevent iron-associated programmed cell death in leukemia, research shows

The article, published in the journal Redox Biology by the group of Dr. Manel Esteller, shows that epigenetic changes prevent iron-associated programmed cell death in leukemia and show a new target for treatment with experimental drugs.
Comunidad Autonoma De Cataluna Lucas Pontel Manel Esteller Emily Henderson Research Professor University Of Barcelona

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New, highly promising strategy to overcome a key cause of cancer deaths

A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.
Andrea Lopez Evripidis Gavathiotis Emily Henderson Nature Communications Cancer Therapeutics Program Albert Einstein College Of Medicine

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.
United Kingdom Comunidad Autonoma De Cataluna Alpha Tauri Eastern Cooperative Oncology Group Nature Medicine Predicting Response

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