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Common endocrine-disrupting chemicals may drive incident hypertension in midlife women

Women exposed to higher concentrations of a class of endocrine-disrupting chemicals known as perfluoroalkyl and polyfluoroalkyl substances are at increased risk for incident hypertension, researchers reported.Data show human exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS) may be associated with higher risk for CVD and peripheral artery disease, as well as several CVD risk factors
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Source: healio.com

Diabetes may worsen longer-term survival for adults with breast cancer

ATLANTA — Presence of diabetes and worse glycemic control were not associated with breast cancer outcomes until 8 years of follow-up, when survival rates worsened for patients with diabetes, according to study data.“In the first 5 years, glycemic control may not be a major contributor to mortality or cancer progression in most individuals with metastatic breast cancer,” Y.M.
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Greater fracture risk seen with insulin vs. metformin use for adults with type 2 diabetes

ATLANTA — Adults with type 2 diabetes who were prescribed insulin had greater risks for major osteoporotic and hip fractures than those prescribed metformin, according to study data.“Patients using insulin or sulfonylurea are at a high risk of fractures compared to metformin-only users, and the risk could be higher in nonobese and well-controlled diabetic patients,” Sung Hye
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Source: healio.com

Monoclonal antibodies have 'good track record' in treating migraines, expert says

DENVER — Monoclonal antibodies have shown promise as an emerging treatment for migraine, Stephanie J. Nahas, MD, MSEd, FAHS, FAAN, said at the American Headache Society annual scientific meeting. “What we've learned from looking back at clinical trial data is that the monoclonal antibodies have very low numbers needed to treat, and very high numbers needed to harm —
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Chemicals found in hair products increase viability of breast cancer cells in Black women

ATLANTA — Parabens, a class of endocrine-disrupting chemicals widely found in hair and personal care products, promote viability and gene expression of a breast cancer cell line in Black women, according to data presented at ENDO 2022. Researchers evaluated the effects of three types of parabens in the HCC1500 breast cancer cell line, which is typically found in Black women of West African
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Source: healio.com

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Future type 1 diabetes therapies, women's CV health among plenary sessions at ENDO 2022

Experts from across the field of endocrinology will gather in Atlanta beginning Saturday for the first in-person Endocrine Society annual meeting in 3 years. ENDO 2022 will kick off Saturday and continue through Tuesday at the Georgia World Congress Center in Atlanta. This year’s meeting will have a hybrid format, with more than 100 sessions livestreamed to a virtual platform for attendees
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Source: healio.com

Relatlimab plus nivolumab confers benefit across key subgroups in advanced melanoma

CHICAGO —Adding relatlimab to nivolumab improved PFS, OS and objective response rates across key subgroups of patients with previously untreated metastatic or unresectable melanoma, according to a study presented at ASCO Annual Meeting.The results showed superiority of nivolumab and relatlimab-rmbw (Opdualag, Bristol Myers Squibb) over single-agent nivolumab (Opdivo, Bristol Myers Squibb),
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Source: healio.com

Dietary changes represent 'growing priority' for GI symptom relief, cancer prevention

We have long known that our diets affect our health, but many questions remain about diet’s impact on conditions like cancer and its potential value in treating a wide variety of health conditions. Two studies presented recently at Digestive Disease Week 2022 shed further light on these connections. Although they examine two different conditions — irritable bowel syndrome and
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Source: healio.com

Sunscreen guide finds concerning ingredients, poor protection in about 75% of products

The Environmental Working Group reported that about 75% of evaluated products rated poorly for skin protection from the sun and include potentially harmful ingredients, according to a press release.The statistic was released as a part of the Environmental Working Group’s (EWG) 16th annual Guide to Sunscreens, which assessed the effectiveness of more than 1,850 products advertising sun
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