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Experts debate obesity vs. glycemic control as primary target for treating type 2 diabetes

NEW ORLEANS — There is no single answer when it comes to determining the primary target for treating type 2 diabetes, two speakers said during a debate at the American Diabetes Association Scientific Sessions. Promoting weight loss to improve health outcomes for people with type 2 diabetes is one of the targets emphasized in the 2022 ADA Standard of Care. Ildiko Lingvay, MD, MPH, MSCS,
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Source: healio.com

Food allergy associated with lower SARS-CoV-2 infection risk

People with food allergies showed lower risk for SARS-CoV-2 infection, whereas those with obesity had a higher risk, according to a study published in The Journal of Allergy and Clinical Immunology. Additionally, results of the perspective surveillance study showed asthma did not positively or negatively impact risk for SARS-CoV-2 infection.
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Dostarlimab shows efficacy as curative-intent treatment in rectal cancer subset

CHICAGO — Dostarlimab, an anti-PD-1 monoclonal antibody, demonstrated a 100% clinical complete response rate among a small cohort of patients with mismatch repair-deficient locally advanced rectal cancer, phase 2 study results showed.Longer follow-up is needed to examine the duration of treatment response in this patient population, according to researchers of the study, reported at ASCO
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Q&A: Pegloticase sustained lower serum urate in kidney transplant recipients with gout

Among kidney transplant recipients with uncontrolled gout, pegloticase showed sustained decreased serum urate levels, according to findings presented at the American Transplant Congress.Patients also showed pain relief and decreased disability without worsening kidney function.
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Dupilumab improves sleep, function in people with chronic rhinosinusitis with nasal polyps

Patients with chronic rhinosinusitis with nasal polyps experienced improved sleep and functioning after 52 weeks of treatment with dupilumab, according to research published in The Journal of Allergy and Clinical Immunology: In Practice. These improvements in turn improved health-related quality of life, William Busse, MD, honorary associate and fellow in the department of medicine, division of
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Source: healio.com

Non-urban stroke patients in New Zealand face poorer outcomes, lack critical care

Patients treated for stroke at non-urban hospitals in New Zealand experience poorer outcomes and face reduced access to crucial stroke interventions across the entire care spectrum, according to a study published in Neurology. “Departures from best practice stroke care in smaller, non-urban New Zealand hospitals have been accepted where a small population is dispersed over a wide geographic
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Disparities in filled opioid use disorder prescriptions linked to COVID-19 pandemic

The COVID-19 pandemic was a likely cause for worsened disparities in buprenorphine and naltrexone access for opioid use disorder among minority groups compared with white patients, per a study published in JAMA Network Open. “Despite some progress in [medications for opioid use disorder] use, pre-pandemic evidence suggested that it was associated with frequent exposure to high out-of-pocket
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