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Potential drivers of chronic allergic inflammation

Potential drivers of chronic allergic inflammation
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United statesRadomir kratchmarovPatrick brennanBrigham division of allergyMass general brighamMassachusetts general hospitalMass eyeBrigham division

Researchers Uncover Potential Causes of Chronic Allergy Inflammation

Researchers Uncover Potential Causes of Chronic Allergy Inflammation
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United statesMaria gutierrez arcelusErinm taylorJoshuaa boyceCaitlinm burkAlanna mcgillBristol myers squibbGarrett dunlapKathleenm buchheitTanyam laidlawDeepaka raoReganw bergmarkRaghup kataruBabakj mehraraRachel roditiEstella lee

Gene expression analyses identify potential drivers of chronic allergic inflammation

Gene expression analyses identify potential drivers of chronic allergic inflammation
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United statesPatrick brennanRadomir kratchmarovBrigham division of allergyMass general brighamMassachusetts general hospitalMass eyeBrigham divisionNature immunology

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

United statesPatrick brennanRadomir kratchmarovDivision of allergyMass general brighamMassachusetts general hospitalMass eyeAtopic dermatitisClinical trialEne expressionImmune responseProgenitor cellsTranscription factorsUlcerative colitis