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USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.
Giorgia Quadrato Sandeep Paul Neil Tedeschi Ranmal Samarasinghe Edward Mallinckdot Jr Carlos Lois

Lab-Grown Human Mini-Brains Show Normal and Abnormal Brain Waves

Ever since scientists began growing mini human brains from stem cells, this sarcastic question has always been asked: โ€œWhat could possibly go wrong?โ€ That one got an answer just last week when mini-brains developed early stages of embryonic eyes that reacted to light. The question scientists respond with is: โ€What could possibly go right?โ€ We... Read more ยป
Bennett Novitch Ranmal Samarasinghe Stem Cell Research Broad Stem Cell Research Center Edythe Broad Center Regenerative Medicine

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