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Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1

Phosphatidylcholine and phosphatidylethanolamine, the two most abundant phospholipids in mammalian cells, are synthesized de novo by the Kennedy pathway from choline and ethanolamine, respectively1–6. Despite the essential roles of these lipids, the mechanisms that enable the cellular uptake of choline and ethanolamine remain unknown. Here we show that the protein encoded by FLVCR1, whose mutation leads to the neurodegenerative syndrome posterior column ataxia and retinitis pigmentosa7&#82...
Clustal Omega Acta Crystallogr Send Energy Aspects Med Lipid Res Acids Res
Source: nature.com

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SGT University Spearheads Sustainable Solutions at the International Conference "RACES-2024" – India Education | Latest Education News | Global Educational News

 The Faculty of Science at Shree Guru Gobind Singh Tricentenary University (SGT University) successfully concluded their two-day International Conference on Recent Advances in Chemical and Environmental Sciences (RACES-2024).The event, which was
Vinod Kumar Jain Prabuddha Ganguli Lakhwinder Singh Green Renewable Energy Tezpur University Doon University

Optimal Therapy Sequencing for Relapsed/Refractory ALL

Dr. Shah and colleagues dissect the social determinants of health, including limited personal resources, frailty, distance to treatment facilities, therapeutic compliance, and other considerations that impact effective treatment sequencing for patients with relapsed or refractory ALL, including access to care and CAR-T cell availability.
Recent Advances Acute Lymphoblastic Leukemia Therapy Sequencing

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