Page 3 - Reporting Trials News Today

This randomized clinical trial examined outcomes of inguinal hernia surgery performed by associate clinicians vs nonspecialist medical doctors among men in Sier

Only 4 of 188 antipsychotic trials assessed blinding, and in all 4 cases, the blind was broken, potentially leading to an overestimation of the drug effect.

This meta-analysis pools data from 7 randomized trials to estimate the association between administration of corticosteroids vs usual care or placebo and all-ca

Jakub G Sobiecki and team aim to develop a biomarker score able to discriminate between Mediterranean diet and habitual diet, and test its association with incident type 2 diabetes in a European cohort.

Hugh Sharma Waddington and colleagues investigate the impacts of water, sanitation and hygiene interventions on all-cause and diarrhoea-related mortality in low- and middle-income countries.

Author summary Why was this study done? Clinical trials are the foundation of evidence-based medicine and should follow established guidelines for transparency: Their results should be available, findable, and accessible regardless of the outcome. Previous studies have shown that many clinical trials fall short of transparency guidelines, which distorts the medical evidence base, creates research waste, and undermines medical decision-making. University Medical Centers (UMCs) play an important...

Background: Suicide is the leading cause of death among Australians. One commonly cited explanation is the impact of social media, in particular, the ways in which young people use social media to communicate about their own experiences and their exposure to suicide-related content posted by others. Guidelines designed to assist mainstream media to safely report about suicide are widespread. Until recently, no guidelines existed that targeted social media or young people. In response, we develop...

In a randomized controlled trial, Runsen Chen and colleagues investigate the impact of a multi-component digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults.

In a 2x2 factorial cluster-randomised controlled trial, Andrew Seal and colleagues evaluate the impact of conditional cash transfers and mHealth audio messaging on childhood malnutrition in internally displaced persons camps in Somalia.

Carl Lachat and colleagues report a a 2×2 factorial individually randomized controlled trial conducted in rural Burkina Faso which investigates the impact of fortified balanced energy-protein supplementation during pregnancy and lactation on infant growth.