Page 4 - Reporting Trials News Today

Study finds bias may be mitigated by female authorship, higher impact factors, registration of trials, and mention of reporting standards.

In a global study of outcome reporting in clinical trials, a research team at The Hospital for Sick Children (SickKids) has issued updated guidelines on what should be included in all trial protocols and published clinical trial reports, with the goal to improve their transparency and utility.

This report, the Consolidated Standards of Reporting Trials (CONSORT)–Outcomes 2022 extension, is a consensus statement on the standards for reporting outcomes

This report, the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT)–Outcomes 2022 extension, is a consensus statement on the standards

In a cluster randomized controlled trial, Shulin Chen and colleagues investigate whether integrated care management of depression and hypertension leads to greater improvements as compared to usual care in older adults attending rural Chinese primary care clinics.

In a randomized trial, Steve M Taylor and colleagues study the effects of 3 malaria chemoprevention regimens on clinical malaria incidence, P. falciparum infection, and dactylitis among children with sickle cell anemia in Kenya.

A review published in JAMA Network Open evaluated 41 RCTs of machine learning interventions. None of the studies fully followed CONSORT-AI standards, a set of guidelines developed for clinical trials evaluating medical interventions that include AI.

Continuous Erector Spinae Plane Block Using Programmed Intermittent Bolus Regimen versus Intravenous Patient-Controlled Opioid Analgesia Within an Enhanced Recovery Program After Open Liver Resection in Patients with Coagulation Disorder: A Randomized, Controlled, Non-Inferiority Trial

This randomized clinical trial evaluates the combination of psychotherapy with psilocybin vs active placebo in patients with alcohol use disorder.

In a randomized controlled trial, Richard A. Bryant and colleagues study the effectiveness of the Early Adolescent Skills for Emotions (EASE) intervention to improve the mental health of Syrian refugees aged 10-14 years living in Jordan.