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June 1, 2021
E-Mail Observational studies have suggested that increased vitamin D levels may protect against COVID-19. However, these studies were inconclusive and possibly subject to confounding. A study published in PLOS Medicine by Guillaume Butler-Laporte and Tomoko Nakanishi at McGill University in Quebec, Canada, and colleagues suggests that genetic evidence does not support vitamin D as a protective measure against COVID-19. The ability of vitamin D to protect against severe COVID-19 illness is of...
May 27, 2021
E-Mail IMAGE: Investigators with the National Institute on Aging, part of the National Institutes of Health, are searching for drug candidates that may correct the brains metabolic abnormalities, such as cholesterol breakdown... view more Credit: Dr. Vijay R. Varma The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimers disease and vascular dementia. However, the underlying mechanisms mediating this relationsh...
May 24, 2021
Share this article CARDIFF, Calif., May 24, 2021 /PRNewswire/ -- A recently published "Research Article" in the Journal of Clinical and Cosmetic Dermatology by Gregory Chernoff, M.D., F.R.C.S.(C) of Chernoff Plastic Surgery, Indianapolis, IN highlights the overwhelming results of a multi-modality platform that has gained popularity and rapid traction in the medical-aesthetics market – The SaltFacial ®. The purpose of the study was to examine the safety and potential efficacy of this new ...
May 24, 2021
E-Mail California state school nutrition policies and federal policies for school meals have mixed impacts on childhood obesity in children of Pacific Islander (PI), Filipino (FI) and American Indian/Alaska native (AIAN) origins, according to a new study published this week in the open access journal PLOS Medicine by Mika Matsuzaki of Johns Hopkins Bloomberg School of Public Health, USA, and colleagues. Children of PI, FI and AIAN origin are some of the most understudied subgroups experienc...
May 10, 2021
E-Mail IMAGE: Researchers at the University of Tokyo examined how lifestyle changes during the COVID-19 state of emergency affected the consumption habits and associated carbon footprints of Japanese households. The carbon footprints... view more Credit: Image by Yin Long, first published in One Earth DOI: 10.1016/j.oneear.2021.03.003 Despite the rapid and significant changes in consumption patterns witnessed during the initial months of the COVID-19 pandemic, Japanese households ma...
April 26, 2021
Abstract Background: Understanding changes in infectiousness during SARS-COV-2 infections is critical to assess the effectiveness of public health measures such as contact tracing. Methods: Here, we develop a novel mechanistic approach to infer the infectiousness profile of SARS-COV-2 infected individuals using data from known infector-infectee pairs. We compare estimates of key epidemiological quantities generated using our mechanistic method with analogous estimates generated using previous a...
April 23, 2021
E-Mail Strenuous efforts to prevent and treat malaria in recent decades have brought great benefits, particularly against disease caused by Plasmodium falciparum in countries in Africa and the Americas. But malaria caused by its "stealthier and more resilient cousin", P. vivax, now needs to be confronted with high priority, say Lorenz von Seidlein and Nicholas White of the Mahidol Oxford Tropical Medicine Research Unit in Bangkok, Thailand in a Perspective. The piece introduces a Collection ...
April 22, 2021
Hanage and Russell conjecture [see also ( 1)] that intermediate levels of immunity may sufficiently restrict within-host viral population size and thus limit adaptive mutations. The evolutionary model in our Research Article encompasses a wide range of scenarios, including the optimistic one Hanage and Russell propose (see scenario 1 in Fig. 4A of the Research Article). However, we also argued that uncertainties in immunodynamics, and in particular evolutionary dynamics of severe acute respirat...
April 22, 2021
PHOTO: RICARDO ARDUENGO/AFP/GETTY IMAGES In their Research Article, “Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes” (this issue, p. 363; published online 9 March), C. M. Saad-Roy et al. write that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine dosing regimens generating intermediate levels of immunity could accelerate the emergence of new variants that are capable of wholly or partially escaping immunity induced by prior infectio...
April 21, 2021
Justin Garwood (Photo provided) SARANAC LAKE — Justin D. Garwood, who grew up in Saranac Lake and moved back with his family last year, recently saw the publication of a book he wrote about classroom management. “Reclaim Your Challenging Classroom” is intended to guide new and veteran teachers in developing effective classroom management techniques, with a particular focus on students with emotional or behavioral disorders and those experiencing trauma. This guide empowers teachers to ...