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Vitamin D may not provide protection from COVID-19 susceptibility or disease severity

 E-Mail Observational studies have suggested that increased vitamin D levels may protect against COVID-19. However, these studies were inconclusive and possibly subject to confounding. A study published in PLOS Medicine by Guillaume Butler-Laporte and Tomoko Nakanishi at McGill University in Quebec, Canada, and colleagues suggests that genetic evidence does not support vitamin D as a protective measure against COVID-19. The ability of vitamin D to protect against severe COVID-19 illness is of...
United Kingdom City Of Guillaume Butler Laporte King College London Clinical Research Facility Lady Davis Institute Of The Jewish

Changes in how cholesterol breaks down in the body may accelerate progression of dementia

 E-Mail IMAGE: Investigators with the National Institute on Aging, part of the National Institutes of Health, are searching for drug candidates that may correct the brains metabolic abnormalities, such as cholesterol breakdown... view more  Credit: Dr. Vijay R. Varma The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimers disease and vascular dementia. However, the underlying mechanisms mediating this relationsh...
National Institutes Of Health United States United Kingdom Lilliana Posey Madhav Thambisetty Vijay Varma

SaltFacial: A Novel Combination Therapy in Aesthetic Medicine and Reconstructive Surgery: Outperforms Old Standards for Aging Skin, Acne, Infection, & Wound Healing

Share this article CARDIFF, Calif., May 24, 2021 /PRNewswire/ --  A recently published "Research Article" in the Journal of Clinical and Cosmetic Dermatology by Gregory Chernoff, M.D., F.R.C.S.(C) of Chernoff Plastic Surgery, Indianapolis, IN highlights the overwhelming results of a multi-modality platform that has gained popularity and rapid traction in the medical-aesthetics market – The SaltFacial ®. The purpose of the study was to examine the safety and potential efficacy of this new ...
Jessica Relyea Gregory Chernoff Research Article Cosmetic Dermatology Chernoff Plastic Surgery Aging Skin Population

Impact of school nutrition policies in California varies by children's ethnicity

 E-Mail California state school nutrition policies and federal policies for school meals have mixed impacts on childhood obesity in children of Pacific Islander (PI), Filipino (FI) and American Indian/Alaska native (AIAN) origins, according to a new study published this week in the open access journal PLOS Medicine by Mika Matsuzaki of Johns Hopkins Bloomberg School of Public Health, USA, and colleagues. Children of PI, FI and AIAN origin are some of the most understudied subgroups experienc...
United States Mika Matsuzaki California Department Of Education Research Article Johns Hopkins Bloomberg School Of Public Health National Heart

Rapid lifestyle changes during early COVID-19 pandemic had no impact on climate change

 E-Mail IMAGE: Researchers at the University of Tokyo examined how lifestyle changes during the COVID-19 state of emergency affected the consumption habits and associated carbon footprints of Japanese households. The carbon footprints... view more  Credit: Image by Yin Long, first published in One Earth DOI: 10.1016/j.oneear.2021.03.003 Despite the rapid and significant changes in consumption patterns witnessed during the initial months of the COVID-19 pandemic, Japanese households ma...
Shibuya Ku Bunkyo Ku Caitlin Devor Keiichiro Kanemoto Alexandros Gasparatos Dabo Guan

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High infectiousness immediately before COVID-19 symptom onset highlights the importance of continued contact tracing

Abstract Background: Understanding changes in infectiousness during SARS-COV-2 infections is critical to assess the effectiveness of public health measures such as contact tracing. Methods: Here, we develop a novel mechanistic approach to infer the infectiousness profile of SARS-COV-2 infected individuals using data from known infector-infectee pairs. We compare estimates of key epidemiological quantities generated using our mechanistic method with analogous estimates generated using previous a...
United Kingdom Nickk Jones Paulz Chen Global Health Action Fund Engineering Research Council Of Canada

A PLOS Medicine Collection on Plasmodium vivax--a neglected cause of malaria

 E-Mail Strenuous efforts to prevent and treat malaria in recent decades have brought great benefits, particularly against disease caused by Plasmodium falciparum in countries in Africa and the Americas. But malaria caused by its "stealthier and more resilient cousin", P. vivax, now needs to be confronted with high priority, say Lorenz von Seidlein and Nicholas White of the Mahidol Oxford Tropical Medicine Research Unit in Bangkok, Thailand in a Perspective. The piece introduces a Collection ...
Krung Thep Mahanakhon Kamala Thriemer Cindy Chu Nicholas White Mahidol Oxford Tropical Medicine Research Unit Research Article

Partial immunity and SARS-CoV-2 mutations—Response

Hanage and Russell conjecture [see also ( 1)] that intermediate levels of immunity may sufficiently restrict within-host viral population size and thus limit adaptive mutations. The evolutionary model in our Research Article encompasses a wide range of scenarios, including the optimistic one Hanage and Russell propose (see scenario 1 in Fig. 4A of the Research Article). However, we also argued that uncertainties in immunodynamics, and in particular evolutionary dynamics of severe acute respirat...
Research Article ஆராய்ச்சி கட்டுரை

Partial immunity and SARS-CoV-2 mutations

PHOTO: RICARDO ARDUENGO/AFP/GETTY IMAGES In their Research Article, “Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes” (this issue, p. 363; published online 9 March), C. M. Saad-Roy et al. write that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine dosing regimens generating intermediate levels of immunity could accelerate the emergence of new variants that are capable of wholly or partially escaping immunity induced by prior infectio...
Research Article ஆராய்ச்சி கட்டுரை

Saranac Laker puts out book on classroom management | News, Sports, Jobs

Justin Garwood (Photo provided) SARANAC LAKE — Justin D. Garwood, who grew up in Saranac Lake and moved back with his family last year, recently saw the publication of a book he wrote about classroom management. “Reclaim Your Challenging Classroom” is intended to guide new and veteran teachers in developing effective classroom management techniques, with a particular focus on students with emotional or behavioral disorders and those experiencing trauma. This guide empowers teachers to ...
United States North Carolina University Of North Carolina Appalachian State University Justind Garwood American Council On Rural Special Education

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