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Practical Issues in Clinical Trials: Starting a trial and logistics​

​​This is the second of six seminars that the LSHTM Clinical Trials Network is running in 2024 on practical issues in clinical trials.  Speakers​Dr Anna Last, LSHTMDr Anna Last is a clinical associate professor from LSHTM, who will present on the logistical considerations and preparation required to conduct a cluster randomised trial, using the example of the MATAMAL trial.
Sylvia Kusemererwa Uganda Research Clinical Trials Network Trials Network Lanna Last Ring Study

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

A vaginal ring containing the antiretroviral drug dapivirine posed no safety concerns when used in the third trimester of pregnancy, according to results to date from the first study of the dapivirine ring during pregnancy and one of only a few studies of an HIV prevention product in pregnant cisgender women.
Mashonaland East South Africa Katherine Bunge Felixg Mhlanga Emily Henderson Johns Hopkins University

South Africa Approves Dapivirine Vaginal Ring for Use by Women | International Partnership For Microbicides

First long-acting HIV prevention product designed specifically for womenApproval paves the way for the monthly ring’s introduction Nearly two-thirds of new adult HIV infections in South Africa occur among womenSILVER SPRING, Md. (March 11, 2022)—The nonprofit International Partnership for Microbicides (IPM) today announced that the monthly dapivirine vaginal ring received
United States United Kingdom Silver Spring Matabeleland North South Africa The Netherlands

IPM's New Drug Application for Dapivirine Vaginal Ring to Reduce HIV Risk in Women Accepted for Filing by US Food and Drug Administration

IPM’s New Drug Application for Dapivirine Vaginal Ring to Reduce HIV Risk in Women Accepted for Filing by US Food and Drug Administration IPM’s New Drug Application for Dapivirine Vaginal Ring to Reduce HIV Risk in Women Accepted for Filing by US Food and Drug Administration SILVER SPRING, Md. (March 3, 2021)—The nonprofit International Partnership for Microbicides (IPM) announced today that the US Food and Drug Administration (FDA) has accepted for review a New Drug Application (NDA) for...
United States United Kingdom South Africa Silver Spring Matabeleland North The Netherlands

WHO recommends dapivirine vaginal ring as a new choice for HIV prevention for women

Date Time WHO recommends dapivirine vaginal ring as a new choice for HIV prevention for women WHO today recommended that the dapivirine vaginal ring (DPV-VR) may be offered as an additional prevention choice for women at substantial risk[1] of HIV infection as part of combination prevention approaches. The DPV-VR is a female-initiated option to reduce the risk of HIV infection. To properly use the ring, it must be worn inside the vagina for a period of 28 days, after which it should be replaced...
Guideline Development Group European Medicines Agency Ring Study Development Group வழிகாட்டல் வளர்ச்சி குழு மோதிரம் படிப்பு

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