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'Split' decision: JAK inhibitors have delivered on only part of their promise

Janus kinase inhibitors have delivered on some, but not all, of the promises that were expected of them upon approval in 2012, a speaker said at EULAR 2022 Congress.“I am trying to bring to you arguments for why particular promises associated with JAK inhibition have been fulfilled and why others have not,” Hendrik Schulze-Koops, MD, of the Ludwig Maximilian University of Munich, said
Rob Volansky Schulze Koopsh Jaki Hendrik Schulze Koops Gilead Sciences Boehringer Ingelheim Biogen International
Source: healio.com

Data find 'direct correlation' between air pollution and osteoporosis, autoimmune disease

There is a “direct correlation” between microscopic particles found in air pollution and increased incidence of osteoporosis and autoimmune disease in a cohort of individuals in Italy, according to a presenter at the EULAR 2022 Congress.“It is estimated that some 3.5 million people die per year simply because of air pollution,” Hendrik Schulze-Koops, MD, of the division of
Rob Volansky Giovanni Adami Hendrik Schulze Koops University Of Verona Ludwig Maximilans University Munich
Source: healio.com

Intestinal mucosal abnormalities shed light on 'viral persistence' of long COVID-19

SAN DIEGO — Patients who recovered from COVID-19 infection demonstrated significant differences in mucosal immune cell populations compared with non-infected controls, according to data presented at Digestive Disease Week 2022. “Our group previously published evidence for the presence of viral proteins in the gut mucosa, not only in patients with acute COVID-19 but also months after
San Diego United States New York Rob Volansky Hadar Meringer Icahn School Of Medicine At Mount Sinai
Source: healio.com

Impacts of 'understudied' calcium pyrophosphate deposition remain unknown

Among the many unanswered questions about calcium pyrophosphate deposition — formerly called “pseudogout” — perhaps the most important is whether it causes osteoarthritis, a speaker said at the Congress of Clinical Rheumatology East.“I am hoping I can drum up some enthusiasm for what really has been an understudied disease, yet very common,” Sara K. Tedeschi,
United States Rob Volansky Sarak Tedeschi American College Of Rheumatology Harvard Medical School Clinical Rheumatology East
Source: healio.com

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'Predicting the future': Emerging technology may help choose right drug at the right time

Remote patient monitoring using novel technology may make it possible for rheumatologists to choose the “right drug right out of the gate,” according to data presented at the Congress of Clinical Rheumatology East.Jeffrey R. Curtis, MD, of the University of Alabama at Birmingham, noted that a wide array of technological advances, from clinical informatics to drug selection using
University Of Alabama At Birmingham United States Rob Volansky Coronna Corevitas Jeffreyr Curtis Eli Lilly
Source: healio.com

'New tools' offer hope for diverse gastrointestinal symptoms in systemic sclerosis

Stepwise interventions, starting with diet and moving on to pharmacotherapies in more severe patients, is essential to managing gastrointestinal complications in scleroderma, a speaker said at the Congress of Clinical Rheumatology East.
United States Rob Volansky Zsuzsanna Mcmahan Phathom Pharmaceuticals Johns Hopkins University School Of Medicine Clinical Rheumatology East
Source: healio.com

'The effects of racism': Patients of color with lupus experience diagnostic delays

People of color with lupus are more likely to experience delayed diagnosis along with greater rates of morbidity and mortality, compared with white patients, according to data. The data were presented at The Future of Systemic Lupus Erythematosus Diagnosis and Treatment meeting, hosted by the University of Texas Southwestern Medical Center, in Dallas.
New York United States University Of Texas Southwestern Medical Center Rob Volansky Weil Cornell Medical College Systemic Lupus Erythematosus Diagnosis
Source: healio.com

Melanoma risk greater in melanocytic lesions with peripheral globules on lower limbs

Melanocytic lesions in the lower extremities that are marked by peripheral globules should be closely watched for melanoma development, according to a study. “Morphology and biology of nevi with peripheral globules are well known, while that of melanomas with peripheral globules remain unclear,” Ana F.A. Moraes, MD, of the department of cutaneous oncology at A.C. Camargo Cancer Center
Rob Volansky Ac Camargo Cancer Center Cancer Center
Source: healio.com

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