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Psilocybin for depression

Current evidence leaves more questions than answers Psilocybin and other psychedelics are under investigation for use in several mental health conditions, including depression.1 Psilocybin, a prodrug that naturally occurs in โ€œmagicโ€ mushrooms (genus Psilocybe ), has been used for ritualistic purposes by indigenous populations of Central-North America for thousands of years.2 Its active metabolite, psilocin, targets 5-hydroxytryptamine type 2A receptors, whose potent activation of serotonergi...
Philipj Cowen Roger Ede Central North America University Of Oxford Department Of Psychiatry Riccardo De Giorgi
Source: bmj.com

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