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Hematoxylin as a killer of CALR mutant cancer cells

Credit: First author Ruochen Jia and Last author Robert Kralovics. Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and group leader at the Medical University of Vienna, have now identified hematoxylin as ...
Czech Republic United States Josef Prchal Radek Skoda Robert Kralovics Ruochen Jia

Hematoxylin compounds can selectively kill CALR mutant cancer cells

Hematoxylin compounds can selectively kill CALR mutant cancer cells Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and group leader at the Medical University of Vienna, have now identified hematoxylin as...
Robert Kralovics Ruochen Jia Emily Henderson University Of Vienna Cemm Research Center Adjunct Principal Investigator

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