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Cadenza Bio Raises $2 44M Series Seed Funding

Remyelinating drug shows potential to improve vision in patients with MS

Remyelinating drug shows potential to improve vision in patients with MS A team led by a biomedical scientist at the University of California, Riverside, reports a drug an estrogen receptor ligand called indazole chloride (IndCl) has the potential to improve vision in patients with multiple sclerosis, or MS. The study, performed on mice induced with a model of MS and the first to investigate IndCl s effect on the pathology and function of the complete afferent visual pathway, is published in Brain Pathology. The afferent visual pathway includes the eyes, optic nerve, and all brain structures responsible for receiving, transmitting, and processing visual information.

Remyelinating drug could improve vision in patients with multiple sclerosis

UC Riverside-led mouse study stresses MS treatment should be started early Author: Iqbal Pittalwala Share This: A team led by a biomedical scientist at the University of California, Riverside, reports a drug an estrogen receptor ligand called indazole chloride (IndCl) has the potential to improve vision in patients with multiple sclerosis, or MS. The study, performed on mice induced with a model of MS and the first to investigate IndCl’s effect on the pathology and function of the complete afferent visual pathway, is published in Brain Pathology. The afferent visual pathway includes the eyes, optic nerve, and all brain structures responsible for receiving, transmitting, and processing visual information.

How This Could Spur Seizures in MS Patients

How This Could Spur Seizures in MS Patients Researchers at the University of California, Riverside School of Medicine have identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures occur in some multiple sclerosis patients. The study was published in While not classically considered a defining symptom of the disease, seizures occur three times more often in MS patients than healthy individuals and may portend a flare-up of symptoms. MS patients that experience seizures also have a decreased quality of life and higher mortality rate. The mechanisms that cause seizures in MS patients remains poorly understood.

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