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The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls—a prospective cohort study | BMC Medicine

The durability of vaccine-induced humoral immunity against SARS-CoV-2 in patients with immune-mediated inflammatory diseases (IMIDs) on immunosuppressive therapy is not known. The aim of this study was to compare the persistence of anti-Spike antibodies following two-dose SARS-CoV-2 vaccination between IMID patients and healthy controls and to identify factors associated with antibody decline. IMID patients on immunosuppressive medication enrolled in the prospective observational Nor-vaC study w...
Division Of Rheumatology Department Of Gastroenterology At Akershus University Hospital Services For Sensitive Data Norwegian Institute Of Public Health Department Of Immunology Oslo University Hospital

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