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This randomized clinical trial evaluates whether helmet noninvasive ventilation compared with usual respiratory support reduces mortality in patients with acute

The aim of this study was to assess antibiotics self-medication practice and associated factors among residents in Dessie City, Ethiopia.

This randomized clinical trial assesses whether high-flow nasal cannula therapy is noninferior to continuous positive airway pressure for time to liberation fro

This randomized clinical trial compares the effect of fluid bolus administration vs no fluid bolus on the incidence of severe hypotension, cardiac arrest, and d

This randomized clinical trial assesses the effect of using weekly electronic patient-reported outcome surveys to monitor symptoms, compared with usual care, on

This randomized trial tested whether intraoperative handovers of care from clinician to another compared with no handover after surgery affected a composite of

This randomized trial assesses whether metformin (vs placebo) given for 5 years would improve invasive disease–free survival and other outcomes in patients with

This randomized trial assesses the effect of robot-assisted radical cystectomy vs open radical cystectomy on number of days patients were alive and out of the h

This pragmatic randomized clinical trial compares the efficacy and adverse events of prone positioning in adults not intubated with acute hypoxemia and COVID-19

This randomized trial assesses the effect of transportation to a local stroke center vs directly to a thrombectomy-capable referral center on 90-day disability